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Showing 1 to 12 of 163 entries
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Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology.

The Journal of antibiotics

Adachi H, Nakae K, Sakamoto S, Nosaka C, Atsumi S, Shibuya M, Higashi N, Nakajima M, Irimura T, Nishimura Y.
PMID: 29089599
J Antibiot (Tokyo). 2017 Nov 01; doi: 10.1038/ja.2017.138. Epub 2017 Nov 01.

Microbial metabolites have attracted increasing interest as a source of therapeutics and as probes for biological mechanisms. New microbial metabolites and derivatives targeted at inflammation and bone disease therapy have been identified by focusing on prostaglandin release, osteoblast differentiation...

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Adachi H, Nakae K, Sakamoto S, et al. Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology. J Antibiot (Tokyo). 2017;doi: 10.1038/ja.2017.138.
Adachi, H., Nakae, K., Sakamoto, S., Nosaka, C., Atsumi, S., Shibuya, M., Higashi, N., Nakajima, M., Irimura, T., & Nishimura, Y. (2017). Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology. The Journal of antibiotics, . https://doi.org/10.1038/ja.2017.138
Adachi, Hayamitsu, et al. "Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology." The Journal of antibiotics vol. (2017). doi: https://doi.org/10.1038/ja.2017.138
Adachi H, Nakae K, Sakamoto S, Nosaka C, Atsumi S, Shibuya M, Higashi N, Nakajima M, Irimura T, Nishimura Y. Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology. J Antibiot (Tokyo). 2017 Nov 01; doi: 10.1038/ja.2017.138. Epub 2017 Nov 01. PMID: 29089599.
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Current landscape and future prospects of antiviral drugs derived from microbial products.

The Journal of antibiotics

Takizawa N, Yamasaki M.
PMID: 29018267
J Antibiot (Tokyo). 2017 Oct 11; doi: 10.1038/ja.2017.115. Epub 2017 Oct 11.

Viral infections are a major global health threat. Over the last 50 years, significant efforts have been devoted to the development of antiviral drugs and great success has been achieved for some viruses. However, other virus infections, such as...

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Takizawa N, Yamasaki M. Current landscape and future prospects of antiviral drugs derived from microbial products. J Antibiot (Tokyo). 2017;doi: 10.1038/ja.2017.115.
Takizawa, N., & Yamasaki, M. (2017). Current landscape and future prospects of antiviral drugs derived from microbial products. The Journal of antibiotics, . https://doi.org/10.1038/ja.2017.115
Takizawa, Naoki, and Yamasaki, Manabu. "Current landscape and future prospects of antiviral drugs derived from microbial products." The Journal of antibiotics vol. (2017). doi: https://doi.org/10.1038/ja.2017.115
Takizawa N, Yamasaki M. Current landscape and future prospects of antiviral drugs derived from microbial products. J Antibiot (Tokyo). 2017 Oct 11; doi: 10.1038/ja.2017.115. Epub 2017 Oct 11. PMID: 29018267; PMCID: PMC7091927.
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Destination of aminoglycoside antibiotics in the 'post-antibiotic era'.

The Journal of antibiotics

Takahashi Y, Igarashi M.
PMID: 29066797
J Antibiot (Tokyo). 2017 Oct 25; doi: 10.1038/ja.2017.117. Epub 2017 Oct 25.

Aminoglycoside antibiotics (AGAs) were developed at the dawn of the antibiotics era and have significantly aided in the treatment of infectious diseases. Aminoglycosides have become one of the four major types of antibiotics in use today and, fortunately, still...

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Takahashi Y, Igarashi M. Destination of aminoglycoside antibiotics in the 'post-antibiotic era'. J Antibiot (Tokyo). 2017;doi: 10.1038/ja.2017.117.
Takahashi, Y., & Igarashi, M. (2017). Destination of aminoglycoside antibiotics in the 'post-antibiotic era'. The Journal of antibiotics, . https://doi.org/10.1038/ja.2017.117
Takahashi, Yoshiaki, and Igarashi, Masayuki. "Destination of aminoglycoside antibiotics in the 'post-antibiotic era'." The Journal of antibiotics vol. (2017). doi: https://doi.org/10.1038/ja.2017.117
Takahashi Y, Igarashi M. Destination of aminoglycoside antibiotics in the 'post-antibiotic era'. J Antibiot (Tokyo). 2017 Oct 25; doi: 10.1038/ja.2017.117. Epub 2017 Oct 25. PMID: 29066797.
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Substance Index for Volume 69.

The Journal of antibiotics

[No authors listed]
PMID: 27994232
J Antibiot (Tokyo). 2016 Dec;69(12):898-900. doi: 10.1038/ja.2016.119.

No abstract available.

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Substance Index for Volume 69. J Antibiot (Tokyo). 2016;69(12):898-900doi: 10.1038/ja.2016.119.
(2016). Substance Index for Volume 69. The Journal of antibiotics, 69(12), 898-900. https://doi.org/10.1038/ja.2016.119
"Substance Index for Volume 69." The Journal of antibiotics vol. 69,12 (2016): 898-900. doi: https://doi.org/10.1038/ja.2016.119
Substance Index for Volume 69. J Antibiot (Tokyo). 2016 Dec;69(12):898-900. doi: 10.1038/ja.2016.119. PMID: 27994232.
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Streptomyces lactacystinicus sp. nov. and Streptomyces cyslabdanicus sp. nov., producing lactacystin and cyslabdan, respectively.

The Journal of antibiotics

Také A, Matsumoto A, Ōmura S, Takahashi Y.
PMID: 26612144
J Antibiot (Tokyo). 2015 Nov;68(11):719. doi: 10.1038/ja.2015.89.

Correction to: The Journal of Antibiotics (2015) 68, 322–327; doi:10.1038/ja.2014.162; published online 10 December 2014. The authors of the above article noticed following error in the publication of this paper. In the Abstract and the "Description of Streptomyces lactacystinicus...

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Také A, Matsumoto A, Ōmura S, et al. Streptomyces lactacystinicus sp. nov. and Streptomyces cyslabdanicus sp. nov., producing lactacystin and cyslabdan, respectively. J Antibiot (Tokyo). 2015;68(11):719doi: 10.1038/ja.2015.89.
Také, A., Matsumoto, A., Ōmura, S., & Takahashi, Y. (2015). Streptomyces lactacystinicus sp. nov. and Streptomyces cyslabdanicus sp. nov., producing lactacystin and cyslabdan, respectively. The Journal of antibiotics, 68(11), 719. https://doi.org/10.1038/ja.2015.89
Také, Akira, et al. "Streptomyces lactacystinicus sp. nov. and Streptomyces cyslabdanicus sp. nov., producing lactacystin and cyslabdan, respectively." The Journal of antibiotics vol. 68,11 (2015): 719. doi: https://doi.org/10.1038/ja.2015.89
Také A, Matsumoto A, Ōmura S, Takahashi Y. Streptomyces lactacystinicus sp. nov. and Streptomyces cyslabdanicus sp. nov., producing lactacystin and cyslabdan, respectively. J Antibiot (Tokyo). 2015 Nov;68(11):719. doi: 10.1038/ja.2015.89. PMID: 26612144.
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Anti-MRSA-acting carbamidocyclophanes H-L from the Vietnamese cyanobacterium Nostoc sp. CAVN2.

The Journal of antibiotics

Preisitsch M, Harmrolfs K, Pham HT, Heiden SE, Füssel A, Wiesner C, Pretsch A, Swiatecka-Hagenbruch M, Niedermeyer TH, Müller R, Mundt S.
PMID: 26412301
J Antibiot (Tokyo). 2015 Sep;68(9):600. doi: 10.1038/ja.2015.79.

Correction to: The Journal of Antibiotics (2015) 68, 165–177; doi:10.1038/ja.2014.118, published online 3 September 2014. The authors noted errors upon publication of this article in the ‘Results and Discussion’ section. The molecular formulas presented for compounds 1–5 in the...

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Preisitsch M, Harmrolfs K, Pham HT, et al. Anti-MRSA-acting carbamidocyclophanes H-L from the Vietnamese cyanobacterium Nostoc sp. CAVN2. J Antibiot (Tokyo). 2015;68(9):600doi: 10.1038/ja.2015.79.
Preisitsch, M., Harmrolfs, K., Pham, H. T., Heiden, S. E., Füssel, A., Wiesner, C., Pretsch, A., Swiatecka-Hagenbruch, M., Niedermeyer, T. H., Müller, R., & Mundt, S. (2015). Anti-MRSA-acting carbamidocyclophanes H-L from the Vietnamese cyanobacterium Nostoc sp. CAVN2. The Journal of antibiotics, 68(9), 600. https://doi.org/10.1038/ja.2015.79
Preisitsch, Michael, et al. "Anti-MRSA-acting carbamidocyclophanes H-L from the Vietnamese cyanobacterium Nostoc sp. CAVN2." The Journal of antibiotics vol. 68,9 (2015): 600. doi: https://doi.org/10.1038/ja.2015.79
Preisitsch M, Harmrolfs K, Pham HT, Heiden SE, Füssel A, Wiesner C, Pretsch A, Swiatecka-Hagenbruch M, Niedermeyer TH, Müller R, Mundt S. Anti-MRSA-acting carbamidocyclophanes H-L from the Vietnamese cyanobacterium Nostoc sp. CAVN2. J Antibiot (Tokyo). 2015 Sep;68(9):600. doi: 10.1038/ja.2015.79. PMID: 26412301.
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Pyridindolols K1 and K2, new alkaloids from Streptomyces sp. K93-0711.

The Journal of antibiotics

Kim YP, Takamatsu S, Hayashi M, Komiyama K, Omura S.
PMID: 9439688
J Antibiot (Tokyo). 1997 Mar;50(3):189-93.

Two new alkaloids with the beta-carboline skeleton, pyridindolols K1 (C18H18N2O5) and K2 (C16H16N2O4), were isolated from the culture broth of Streptomyces sp. K93-0711. The structure of pyridindolols were established by spectroscopic investigations and chemical transformations. Pyridindolol K2 inhibited the...

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Kim YP, Takamatsu S, Hayashi M, et al. Pyridindolols K1 and K2, new alkaloids from Streptomyces sp. K93-0711. J Antibiot (Tokyo). 1997;50(3):189-93
Kim, Y. P., Takamatsu, S., Hayashi, M., Komiyama, K., & Omura, S. (1997). Pyridindolols K1 and K2, new alkaloids from Streptomyces sp. K93-0711. The Journal of antibiotics, 50(3), 189-93.
Kim, et al. "Pyridindolols K1 and K2, new alkaloids from Streptomyces sp. K93-0711." The Journal of antibiotics vol. 50,3 (1997): 189-93.
Kim YP, Takamatsu S, Hayashi M, Komiyama K, Omura S. Pyridindolols K1 and K2, new alkaloids from Streptomyces sp. K93-0711. J Antibiot (Tokyo). 1997 Mar;50(3):189-93. PMID: 9439688.
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Malolactomycins C and D, new 40-membered macrolides active against Botrytis.

The Journal of antibiotics

Tanaka Y, Yoshida H, Enomoto Y, Shiomi K, Shinose M, Takahashi Y, Liu JR, Omura S.
PMID: 9439689
J Antibiot (Tokyo). 1997 Mar;50(3):194-200.

A strain of Streptomyces was found to produce two new components of the 40-membered ring macrolides, malolactomycins C and D. They inhibited the growth of Botrytis cinerea in an agar medium and a detached leaf method.

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Tanaka Y, Yoshida H, Enomoto Y, et al. Malolactomycins C and D, new 40-membered macrolides active against Botrytis. J Antibiot (Tokyo). 1997;50(3):194-200
Tanaka, Y., Yoshida, H., Enomoto, Y., Shiomi, K., Shinose, M., Takahashi, Y., Liu, J. R., & Omura, S. (1997). Malolactomycins C and D, new 40-membered macrolides active against Botrytis. The Journal of antibiotics, 50(3), 194-200.
Tanaka, et al. "Malolactomycins C and D, new 40-membered macrolides active against Botrytis." The Journal of antibiotics vol. 50,3 (1997): 194-200.
Tanaka Y, Yoshida H, Enomoto Y, Shiomi K, Shinose M, Takahashi Y, Liu JR, Omura S. Malolactomycins C and D, new 40-membered macrolides active against Botrytis. J Antibiot (Tokyo). 1997 Mar;50(3):194-200. PMID: 9439689.
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Novel C-2 substituted carbapenem derivatives. Part III. Synthesis and biological activity of 2-(functionalised ethenyl, oxyiminomethyl and alpha-.

The Journal of antibiotics

Clear NJ, Davies JS, Eglington AJ, Fell SC, Hinks JD, Hird NW, Hunt E, Moss SF, Pearson MJ.
PMID: 9439695
J Antibiot (Tokyo). 1997 Mar;50(3):237-45.

The synthesis, antibacterial activity and stability to human dehydropeptidase-1 (DHP-1) of three small series of carbapenems carrying carbon-linked substituents at C-2 are described. C-2 Ethenyl carbapenems showed moderate antibacterial activity but poor stability to DHP-1. C-2 Oxyiminomethyl carbapenems demonstrated...

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Clear NJ, Davies JS, Eglington AJ, et al. Novel C-2 substituted carbapenem derivatives. Part III. Synthesis and biological activity of 2-(functionalised ethenyl, oxyiminomethyl and alpha-. J Antibiot (Tokyo). 1997;50(3):237-45
Clear, N. J., Davies, J. S., Eglington, A. J., Fell, S. C., Hinks, J. D., Hird, N. W., Hunt, E., Moss, S. F., & Pearson, M. J. (1997). Novel C-2 substituted carbapenem derivatives. Part III. Synthesis and biological activity of 2-(functionalised ethenyl, oxyiminomethyl and alpha-. The Journal of antibiotics, 50(3), 237-45.
Clear, et al. "Novel C-2 substituted carbapenem derivatives. Part III. Synthesis and biological activity of 2-(functionalised ethenyl, oxyiminomethyl and alpha-." The Journal of antibiotics vol. 50,3 (1997): 237-45.
Clear NJ, Davies JS, Eglington AJ, Fell SC, Hinks JD, Hird NW, Hunt E, Moss SF, Pearson MJ. Novel C-2 substituted carbapenem derivatives. Part III. Synthesis and biological activity of 2-(functionalised ethenyl, oxyiminomethyl and alpha-. J Antibiot (Tokyo). 1997 Mar;50(3):237-45. PMID: 9439695.
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Identification of preussin as a selective inhibitor for cell growth of the fission yeast ts mutants defective in Cdc2-regulatory genes.

The Journal of antibiotics

Kasahara K, Yoshida M, Eishima J, Takesako K, Beppu T, Horinouchi S.
PMID: 9439701
J Antibiot (Tokyo). 1997 Mar;50(3):267-9.

No abstract available.

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Kasahara K, Yoshida M, Eishima J, et al. Identification of preussin as a selective inhibitor for cell growth of the fission yeast ts mutants defective in Cdc2-regulatory genes. J Antibiot (Tokyo). 1997;50(3):267-9
Kasahara, K., Yoshida, M., Eishima, J., Takesako, K., Beppu, T., & Horinouchi, S. (1997). Identification of preussin as a selective inhibitor for cell growth of the fission yeast ts mutants defective in Cdc2-regulatory genes. The Journal of antibiotics, 50(3), 267-9.
Kasahara, et al. "Identification of preussin as a selective inhibitor for cell growth of the fission yeast ts mutants defective in Cdc2-regulatory genes." The Journal of antibiotics vol. 50,3 (1997): 267-9.
Kasahara K, Yoshida M, Eishima J, Takesako K, Beppu T, Horinouchi S. Identification of preussin as a selective inhibitor for cell growth of the fission yeast ts mutants defective in Cdc2-regulatory genes. J Antibiot (Tokyo). 1997 Mar;50(3):267-9. PMID: 9439701.
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Tripeptide LY301621 and its diastereomers as methicillin potentiators against methicillin resistant Staphylococcus aureus.

The Journal of antibiotics

Eid CN, Halligan NG, Nicas TI, Mullen DL, Butler TF, Loncharich RJ, Paschal JW, Schofield CJ, Westwood NJ, Cheng L.
PMID: 9439706
J Antibiot (Tokyo). 1997 Mar;50(3):283-5.

No abstract available.

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Eid CN, Halligan NG, Nicas TI, et al. Tripeptide LY301621 and its diastereomers as methicillin potentiators against methicillin resistant Staphylococcus aureus. J Antibiot (Tokyo). 1997;50(3):283-5
Eid, C. N., Halligan, N. G., Nicas, T. I., Mullen, D. L., Butler, T. F., Loncharich, R. J., Paschal, J. W., Schofield, C. J., Westwood, N. J., & Cheng, L. (1997). Tripeptide LY301621 and its diastereomers as methicillin potentiators against methicillin resistant Staphylococcus aureus. The Journal of antibiotics, 50(3), 283-5.
Eid, et al. "Tripeptide LY301621 and its diastereomers as methicillin potentiators against methicillin resistant Staphylococcus aureus." The Journal of antibiotics vol. 50,3 (1997): 283-5.
Eid CN, Halligan NG, Nicas TI, Mullen DL, Butler TF, Loncharich RJ, Paschal JW, Schofield CJ, Westwood NJ, Cheng L. Tripeptide LY301621 and its diastereomers as methicillin potentiators against methicillin resistant Staphylococcus aureus. J Antibiot (Tokyo). 1997 Mar;50(3):283-5. PMID: 9439706.
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A search for Pseudomonas alginate biosynthesis inhibitors from microbial metabolites.

The Journal of antibiotics

Nakagawa A, Hosoyama T, Chubachi K, Takahashi S, Ohkubo T, Iyobe S.
PMID: 9439707
J Antibiot (Tokyo). 1997 Mar;50(3):286-8.

No abstract available.

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Nakagawa A, Hosoyama T, Chubachi K, et al. A search for Pseudomonas alginate biosynthesis inhibitors from microbial metabolites. J Antibiot (Tokyo). 1997;50(3):286-8
Nakagawa, A., Hosoyama, T., Chubachi, K., Takahashi, S., Ohkubo, T., & Iyobe, S. (1997). A search for Pseudomonas alginate biosynthesis inhibitors from microbial metabolites. The Journal of antibiotics, 50(3), 286-8.
Nakagawa, et al. "A search for Pseudomonas alginate biosynthesis inhibitors from microbial metabolites." The Journal of antibiotics vol. 50,3 (1997): 286-8.
Nakagawa A, Hosoyama T, Chubachi K, Takahashi S, Ohkubo T, Iyobe S. A search for Pseudomonas alginate biosynthesis inhibitors from microbial metabolites. J Antibiot (Tokyo). 1997 Mar;50(3):286-8. PMID: 9439707.
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Showing 1 to 12 of 163 entries